Friday, 19 December 2014

New 'Game-Changing' Heart Drug. Or new threat to our health

Pulse announced today (19th December 2014) that a new 'game-changing' heart drug was to be fast-tracked through the drug approval system. The drug is called LCZ696 and is being developed by Novartis. It is a combination of two 'antihypertensive' drugs, Valsartan (Diovan), an 'angiotension II receptor blocker, and a new drug, Sacubitril, a 'neprilysis inhibitor'.

So, as with most conventional medical drugs, the purpose and function of the new drug is to 'block' and 'inhibit' bodily functions

As a result, I predict danger, and massive harm to the patients who will be given this drug, probably as soon as September 2015. But, of course, I could be wrong! This could be a first for the Big Pharma industry - a safe drug - that actually works.

But this is not the usual process. Normally, drugs are introduced by pharmaceutical companies as 'game-changing', and doctors, the NHS parrot these hopes, and the media comply with such assessments, without question. Then, reality begins to dawn!

  • Soon, 'side-effects' are noted. Then 'adverse reactions'. These are downplayed, balanced by some game of 'risk-benefit' analysis.
  • Then, when the harm the drug is causing becomes more obvious, drug regulators place them under restriction, and place 'black-box' warnings on the packaging. But the drug is too profitable, and doctors who have prescribed it are reluctant to admit that they may have damaged their patients. So it is kept on sale, and the suffering continues.
  • Then, the harm caused by the drug begins to clearly outweigh any possible benefits, which it has been found anyway, have been severely over-hyped.
  • So the drug is withdrawn, as quietly as possible. Or on some occasions, drug regulators will actually ban it. 

I have described this process elsewhere. Will this new 'wonder drug' fit into this regular, too predictable pattern? I intend to follow and report on the progress of this drug on this blog over the next few years - so we will see!

But the signs are not good. Both drugs restrict, interfare and meddle with the normal functioning of the body. Fast-tracked drugs have had, in the past, an even worse record then those that go through the normal process. And Valsartan, one of the drugs used in this new combination, already has a record of serious 'disease-inducing effects'.

Valsartan (Diovan).
Shortness of breath, pounding heartbeat (or weak pulse and slow heart rate), fluttering in the chest, weakness, confusion, rapid weight gain, fainting, muscle weakness, headache, dizziness, flu symptoms, nausea, stomach pains, diarrhoea, back pain, blurred vision, skin rash - et al.

And as Wikipedia has already pointed out, tests on this new drug have already identified that the problems are likely to be similar to all antihypertensive drugs.

"Common adverse effects the main study were cough, hyperkalemia (high potassium levels in the blood, which can be caused by valsartan), renal dysfunction, and hypotension (low blood pressure, a common side effect of antihypertensives). 12% of the patients withdrew from the study during the run-in phase because of such events."

Yet the European Medicines Agency (EMA) are happy to fast-track new drugs if "the medicine is expected to be of major public health interest particularly from the point of view of therapeutic innovation".
In the Pulse article it outlines what Novartis are saying about the new drug, prior to launch.
"Treatment with LCZ696 was shown to significantly reduce cardiovascular deaths and heart failure hospitalisations when compared with 'gold-standard' treatment....." with other drugs.
Pulse report that 'GP experts' have told them that the "drug could be a ‘game changer’ in the management of heart failure, because it appears to be so much more effective than established treatments".

So LCZ696 is really something for us all to look forward to! It is already being proclaimed as another triumph for the conventional medical establishment, who cannot get it to us quickly enough! And naturally, nowhere in the article is anything mentioned about side-effects, adverse reactions, or disease inducing reactions to the drug!

So, just watch this space over the next few years, and we will see whether the hype of the conventional medical establishment, backed by Big Pharma funding, is correct. Or whether my more mundane prediction is more accurate!

Thursday, 11 December 2014

The rise of Superbugs. The failure of conventional medicine

It has been reported that 'drug-resistant infections' will kill an extra 10 million people a year worldwide by 2050 - more deaths than currently caused by cancer apparently.  Already, it is estimated that they are causing about 700,000 deaths per year.

Jim O'Neill, who was appointed by the Prime Minister to review the problem of antimicrobial resistance, has also estimated that the costs of this disaster would be around £63 trillion.

The deaths would be caused by the many new Superbugs, and by resistance to drugs once thought capable of treating diseases such as Malaria, E-Coli and TB. As a result he predicts serious population reduction, and a large reduction of economic output. But many surgical interventions, such as joint replacements, transplant surgery, Caesarian sections, et al, will also be affected as they rely on antibiotics to prevent infections.

So what is the conclusion reached about this pending health disaster?

More and better drugs, and using these drugs in a way that will reduce the rise of resistance! Yes, the very cause of this potential disaster is seen as its solution! Indeed, some might say that this is a triumph of hope over experience! O'Neill has apparently said that some scientists were more concerned about this problem than they were about climate change.

Presumably, in order to tackle climate change, the strategy of these scientists will be to burn more fossil fuels, and to increase the amount of carbon and greenhouse gases into the atmosphere!

So if antibiotics has led to the creation of superbugs, we just need new antibiotics. The warfare waged between our bodies and the chemicals we have developed to fight and destroy many different organisms (that mostly live quite happy around and within our bodies) is to be intensified! The assumption must be that we can develop drugs so powerful the bugs and bacteria and viruses that attack us will not be able to resist anymore.

The problem with such a bellicose medical strategy is quite simple - will we ourselves be able to survive such an onslaught by Big Pharma chemical?

The lesson we need to learn is quite different - that the maintenance of health, and the recovery of good health, is not a battle between what is happening within our bodies and the efforts of the conventional medical establishment to control it. The bugs, the microbes, the viruses which the pharmaceutical companies have fought to destroy are actually part of us. We have, I believe, always lived quite happily and peacefully with MRSA until antibiotics sought to destroy it. Now, it would seem, it has evolved in a ways that can destroy us!

This is the main lesson that alternative medical therapies teaches us. Homeopathy, Herbalism, Acupuncture, Reflexology, et al, all recognise that life, and good health, is not a battle, a declaration of war against the elements that surround, and are part of us. It is all a matter of co-operation and balance. We don't need drugs that are 'anti-' anything. We don't need drugs that 'suppress' or 'block' or 'inhibit' the natural functions of our bodies.

Whatever it is that we attack with drugs will resist, adapt, and change, to such an extent that we will no longer be able to live in harmony with them. What conventional medicine has sought to do for centuries, but particularly over the last 100 years, is a road leading to inevitable disaster.

So more of the same will not help us prevent the impending disaster being predicted. What is necessary is to recognise why conventional, drug-based medicine, has been a mistake, a wrong turn, and the cause of the disaster, not its solution.

The science that has transformed our world, in terms of travel, communications, technology, and much else over the last 100 years and more, has failed to transform our health. Why? It has failed disastrously because it has never recognised the basis of illness. It studied the sick body, analysed meticulously what was happening within it, but then mistook the body's reaction to disease with the disease itself! It was, and continues to be, a fundamental mistake.

What science has so brilliantly observed was the body trying to heal itself! Fever, for example, is in most cases a defence mechanism, not a threat to health. In many similar ways, particularly with the bacteria and viruses that live alongside us, what medical science observed within the sick body was not necessarily an enemy, but a friend that should not have been attacked and destroyed. Effectively, conventional medicine has made an enemy from what should have been an ally.

In the years to come, good health is likely to become the preserve of those who recognise the difference between working alongside the body, and its incredible ability to heal itself through its immune system, and a now dominant medical system that sees illness and disease as something that has to be fought and destroyed.

The failure of antibiotics, as with the failure of all conventional drugs over the last century, is not a disaster. It is an inevitable consequence of conventional medicine's failure to understand that to live in harmony, and in good health with our world, we have to stop attacking it!

The solution to drug resistance is not more drugs. It is to discard drugs, to recognise their failure, and to move towards adopting gentler, safer, more effective medical therapies.

50% of population now on drugs that cause disease

The Health Survey for England seeks to monitor trends in the nation’s health. It has carried out a Health Survey for England each year since 1994. For their 2013 survey 8,795 adults and 2,185 children were interviewed. This year's survey, recently published, comes to these amazing conclusion, highlighting the amount of drug taking now prevalent within the UK.

  • "43% of men and 50% of women reported that they had taken at least one prescribed medicine in the last week. 
  • 22% of men and 24% of women reported that they had taken at least three prescribed medicines in the last week. 
  • This proportion increased with age, with more than half of participants aged 65-74 and more than 70 per cent of those aged 75 and over having taken at least three prescribed medicines.

The Conventional Medical Establishment (the NHS, and our GPs) agree that each of these drugs cause side-effects and 'adverse reactions'. What is not admitted is that these 'side-effects' and 'adverse reactions' are, in truth diseases. Let's reflect on what this means.

  • Pharmaceutical drugs are causing 'side-effects' (that is, creating disease) in 43% of men, and 50% of women. 
  • That percentage of people taking multiple drugs are likely to be suffering from more 'side-effects' (disease) not just from each drug, but from the unknown consequences of taking more than one drug - polypharmacy.
  • Older people, those whose bodies are less likely to withstand the assault made on them by these drugs, are most at risk of polypharmacy.

One doctor, interviewed by the BBC Today programme this morning (11th December 2014) said that this was a good thing, because the drug were 'preventing future disease'. Naturally, the BBC allowed him to get away with this bland re-assurance, a subterfuge so often practiced by conventional medicine.

  • Drugs and vaccines are good for us!
  • We are healthier, and living longer, because we have access to pharmaceutical drugs!
  • There are no dangers to taking prescribed drugs!
The dangers of conventional drugs and vaccines are rarely, if ever discussed. So it is small wonder that so many people take them, thinking (as they have been told) that they keep them health, and not knowing the full enormity of the harm they cause.

So we now experience disease at epidemic proportions, some of them diseases that have only been known since pharmaceutical drug taking took off with the NHS in the late 1940's, 1950's onwards.

Autism, Alzheimers, Arthritis, Asthma, Cancer, Crohns, Diabetes, Depression, Eczema, Epilepsy, Heart Disease, ME, Ulcerative Colitis, and so many more.

And for each of these diseases, one of the known causes are the prescribed drugs that so many people are now taking. Some of these known causes are admitted by the Conventional Medical Establishment. Some are actually named after the drug that caused the disease - see, for example, Steroid Induced Diabetes. Most, of course, are denied. 

But it is becoming increasingly difficult to ignore the 'disease-inducing-effects', or DIEs of pharmaceutical drugs. One of the commonest drugs being prescribed are Statin drugs. Doctors continue to tell us they are 'entirely safe', and our media will not question this; but these drugs are  known to cause:
  • Muscle damage
  • Diabetes
  • Cataracts
  • Kidney damage
  • Liver failure
The Health Survey showed that 40 million prescriptions of Simvastatin, the most 'popular' Statin drug, were made in one year. What proportion of these patients would need to develop any of the above DIEs before it caused an epidemic? How many of these would then need some other form of drug to correct the 'side-effect'? And what 'side-effects' would these drugs cause?

We are not told! We do not know because we do not ask. Our mainstream media is asleep, content to parrot the excuses of the conventional medical establishment. Big Pharma are never challenged. Perhaps they are too big to fail, to powerful to challenge.

So the NHS is in financial difficult, once again. GP's need more money. Hospitals need more money. And the political parties are once more in the process of out-bidding each other before the General Election. "We will spend more than they will!" So more money will be spent on more drugs and vaccines, and the additional DIEs this creates will, in a short time, create another funding crisis, with more demands for more spending.

Until, that is, we begin to recognise the the Conventional Medical System is failing, failing badly, and is making us sicker the more it medicates us.

Friday, 28 November 2014

Vaccines Don't Cause Autism (?). Listen, you fools (!)

Vaccines don't cause Autism!


Are you listening? How many more times must you all be told by the Conventional Medical Establishment?

Just listen, and be told!

Doctor's tell us they are safe. The NHS tells us. The government urges us to protect ourselves by accepting vaccines. Our mainstream media stays silent and regularly lets us know about the promotion campaigns of the Pharmaceutical companies (Big Pharma).

Yet still, despite all this, these parents keep telling us that their previously 'normal' children became victims to Autism, and other diseases, after they had a vaccination. See here, fore example.

There are so many of these personal testimonies, so many such family tragedies. Many, many more are not known about, because parents accept what they have been told. Vaccines do not cause Autism. VACCINES DO NOT CAUSE AUTISM.

So the fact that the epidemic rise in Autism over the last 40-50 years, a condition unknown until the 1940's, 1950's, closely  mirrors the rise and rise of vaccines during the same period, is just coincidence, 'bad luck', and misfortune.

Autism just happens. There is no cause.

And if vaccines are the cause of epidemic Autism, the Conventional Medical Establishment, would surely not hide it from us? And if they did, our Media would investigate it - surely?

Tuesday, 4 November 2014

Viagra? An erection at any cost to our health?

Okay. I know this drug is not only popular, it is the cause of much mirth! It is, of course, a drug used for male impotence, or erectile dysfunction. Indeed, it is widely used ‘recreationally’ by men who want to improve their sexual performance, and to increase the size of their erection. 

There is a widespread belief that it is effective in doing this, although the evidence for this remains less than certain.

Yet what most men don’t realise is that this drug has a multitude of adverse reactions, not often spoken about - many of which can actually damage male potency, and fertility, not to mention our general health. 

Just by listing them here makes this a large article! 

Most common reactions
Aches or pains in the muscles
Bloody nose
Difficult or laboured breathing
Pain or tenderness around the eyes and cheekbones
Redness of the skin
Stomach discomfort following meals
Stuffy or runny nose
Trouble sleeping
Unusually warm skin

Less common reactions
Bladder pain
Burning feeling in the chest or stomach
Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
Cloudy or bloody urine
Increased frequency of urination
Pain on urination
Stomach upset
Tenderness in the stomach area

Rare reactions
Abdominal or stomach pain
Abnormal visions
Abnormal dreams
Behaviour change similar to drunkenness
Bleeding of the eye
Blurred vision
Bone pain
Breast enlargement
Chest pain
Clumsiness or unsteadiness
Cold Sweats
Convulsions (Seizures)
Cool or pale skin
Deafness and hearing loss
Decrease in amount of urine, or frequency of urination
Decreased vision
Diarrhoea or stomach cramps (severe or continuing)
Difficulty concentrating
Difficulty in swallowing
Dizziness or lightheadedness, especially when getting up from a lying or sitting position suddenly
Double vision
Dry eyes
Dry mouth
Dryness, redness, scaling, or peeling of the skin
Ear pain
Excessive hunger
Eye pain
Fainting or faintness
Fast, irregular, or pounding heartbeat
Feeling of something in the eye
Fever or chills
Headache (severe or continuing)
Increased amount of saliva
Increase in size of the pupil
Increased skin sensitivity
Increased sweating
Increased thirst
Lack of coordination
Loss of bladder control
Lower back or side pain
Mental depression
Migraine headache
Nausea (severe or continuing)
Numbness of the hands
Numbness or tingling of the hands, legs, or feet
Painful, swollen joints
Prolonged, painful erection of penis
Rectal bleeding
Redness or irritation of the tongue
Redness, soreness, swelling, or bleeding of the gums
Redness, burning, or swelling of the eyes
Redness, itching, or tearing of the eyes
Restless sleep
Ringing or buzzing in the ears
Seeing shades of colours differently than before
Sensation of motion, usually whirling, either of one's self or of one's surroundings
Sensitivity to light
Sexual problems in men (continuing), including failure to experience a sexual orgasm
Skin lesions with swelling
Skin paleness
Skin rash, hives, or itching
Skin ulcers
Slurred speech
Sore throat
Sores in the mouth and on the lips
Sudden weakness
Swelling of the face, hands, feet, or lower legs
Tense muscles
Trembling and shaking
Trouble breathing
Twitching of the muscles
Unusual feeling of burning or stinging of the skin
Unusual tiredness or weakness
Vision changes
Vision loss, temporary
Waking to urinate at night
Worsening of asthma

Incidence not known (!!)

It’s a big price to pay for a slightly larger erection!

The Dangers of Common Painkilling Drugs (NSAID drugs)

Non Steroidal anti-inflamatory drugs (NSAID) are painkilling drugs with analgesic and anti-inflammatory effects. They are used to reduce pain, fever and inflammation. People have taken NSAIDs to obtain temporary relief from pain for decades, and continue to do so - usually without knowing, or being told, just how harmful they can be to our health.
Your doctor will often prescribe these drugs for many conditions, including arthritis, rheumatism, sciatica, back pain, headache, migraine, sprains, strains, dental pain, post-operative pain, menstrual pain, and to reduce temperature. And sometimes, people will get stuck on these drugs for many years as conventional medicine often has nothing else to offer. And we take them without knowing the harm that they can do to us.
Moreover, NSAID painkillers are readily available as 'over-the-counter' (OTC) drugs that most people widely considered to be safe to use. They included many of the commonest painkillers, such as Aspirin, Ibuprofen and Paracetomol. Indeed, their ready availability makes them not only popular, but masks the many important contra-indications to taking them!
However, the fact that these drugs are common and well-known does not make them safe. Far from it. It is now well established that that they cause gastro-intestinal bleeding, renal problems, and increase the risk of heart problems. Most of the major damage caused relates to their effects on the stomach and bowels (Abdominal bleedings, pain, diarrhea, and stomach ulceration. It is estimated that about 10%-50% of people are unable to tolerate NSAID treatment because of their side effects, and that some 15% of people on long-term NSAID treatment develop a peptic ulcers.
Common adverse reactions include Headache, Nausea, Diarrhea, Constipation, Excess gas, Extreme weakness and fatigue, 
More serious adverse reactions to NSAID drugs include muscle cramps, numbness and tingling, abdominal cramps, heartburn, indigestion, rapid weight gain, black or bloody stools, bloody urine or vomit, allergic reactions, such as difficulty breathing, hives, swelling of the lips, the tongue or face, decreased hearing or ringing in the ears (tinnitus).

Common NSAID painkillers, such as ibuprofen, are also associated now with heart conditions. One study showed that NSAID drugs caused a 30% increased risk of the first hospital admission for heart failure ( 
Indeed, NDSAID’s may cause an increased risk of serious cardiovascular events, hypertension, myocardial infarction, congestive heart failure, and stroke, which can be fatal; and these risks increase the longer the drugs are used.

Ankylosing Spondylitis? Homeopathy or Conventional Drugs?

Ankylosing spondylitis (or AS) is a long-term or chronic condition in which the spine and other areas of the body become inflamed. NHS Choices state that the symptoms of AS can vary but usually involve:

    * back pain and stiffness that improves with exercise and is not relieved by rest.
    * pain and swelling in other parts of the body, such as the hips, knees and ribs.
    * fatigue (extreme tiredness).

These symptoms tend to develop gradually, usually over several months or years, and may come and go over time.

Conventional Medical Treatment
NHS Choices says this about conventional medical treatment for AS

“There is no cure for ankylosing spondylitis (AS), but treatment is available to help relieve the symptoms. Treatment can also help delay or prevent the process of the spine fusing (joining up) and stiffening. In most cases, treatment will involve a combination of exercise, physiotherapy and medication.....” 

The treatments outlined by NHS Choices are:

1. Physiotherapy an Exercise.

2. Painkillers
These include NSAID painkillers, Paracetamol, and Codeine, all of which have serious adverse reactions, especially if taken over a long period of time. Click on each one, above, to see a description of the dangers of these painkillers. 

3. Anti-TNF Medication.
Apparently only used if painkillers do not work, and “their long-term effects are unknown”. NICE (National Institute for Health and Care Excellence) have produced guidelines limiting their use, as this description in NHS Choices indicates how cautious (and therefore how dangerous) these drugs can be.

“If your rheumatologist recommends using anti-TNF medication, the decision about whether they are right for you must be discussed carefully and your progress will be closely monitored. This is because anti-TNF medication can interfere with the immune system (the body’s natural defence system), increasing your risk of developing potentially serious infections”.

Steroid drugs also need to be recognised for the harm they can do. Click on the link for an explanation of the dangers of Corticosteroids.

5. Disease-Modifying Anti-Rheumatic Drugs
NHS Choices says that DMARD drugs are an alternative type of medication often used to treat other types of arthritis, but may be prescribed for AS, “although they are only beneficial in treating pain and inflammation in joints in areas of the body other than the spine”. NHS Choices make no comment about the adverse reactions to these drugs.

6. Surgery
NHS Choices says that in cases where a joint has become severely damaged, joint replacement surgery may be recommended to improve pain and movement in the affect joint. It also says that in rare cases, corrective surgery may be needed if the spine becomes badly bent.

The Homeopathic Treatment of Ankylosing Spondylitis
Important Note. 
Homeopathy does not treat illness or diseases. It treats the individual who has been diagnosed with a particular illness or disease. The distinction is important, and if you wish to read more about this, click on the chapter “Illness Diagnosis” above. 

Homeopathy provides an alternative to conventional medical treatment of AS, and is, of course, a lot safer.

One excellent description of the homeopathic treatment of AS can be found on Dr Nancy Malik’s website (see Homeopathy and Ankylosing Spondylitis). Here are brief descriptions of some of the remedies that are often used in the treatment of AS.

Aesculus hippocastanum
Important remedy in ankylosing spondylitis. Marked stiffness and pain over the sacroiliac joint. Worse: Rising from a seat or from stooping.

Aurum metallicum
Serious or advanced rheumatism with marked stiffness. Rheumatism with stiffness or spasms of the chest wall. Severe spasm or tearing pains. Pains also described as “paralytic.” An important remedy in ankylosing spondylitis. Wandering arthritis; moving spot to spot from one week to next. Worse: Night. Morning in bed. Hip pain worse rising from a seat or from walking. Chest wall pain and spasm worse first motion and inspiring. Better: Motion. Location: Wandering arthritis. Back. Chest and ribs. Hip.

Bacillus 7
Sensation of stiffness and ankylosis of the articulations. Shoulders painful, stiff, movements limited and difficult. Dorsal pains, aggravated by movements. Pains of all the articulations, drawing with the sensation of being drawn and rigid, aggravated when waking up after a long rest. Aponeurotic and ligamentary retraction.

Butyricum acidum
Morbus coxae senilis. Ankylosing spondylitis. Tired feeling and dull pain in small of back, worse walking. Pain in ankles and up back of leg. Pain low down in back and limbs.

Colchicum autumnale
Pain with ankylosis of the back and neck. Burning pain in the neck, ameliorated by movement. Pain in the renal region. Pain in the left scapula, aggravated on waking, by movement, and by lying on the left side. Ankylosing arthritis of the vertebral joints. Non-inflammatory chronic rheumatism of the hip and knee.

Cuprum metallicum
Cramps in calves and soles. Jerking, twitching of muscles in hands and feet. Clenching of thumb in palms. Cramps in palms, calves and soles. Coldness of hands. Joints contracted. Great weariness of limbs. Ankles painfully heavy. Ankylosis of shoulder joint. Knees double up involuntary when walking, bringing him down.

Fatigue and rheumatic pains in the limbs, and legs feel like rubber. Heaviness in the calves. Stiffness at the nape of the neck , with pain starting at the 7th cervical vertebra, spreading up the nape and accompanied by right frontal hemicrania. Pain between the shoulders. Pain in the right shoulder, spreading towards the neck. Dorsal pain and stiffness, like ankylosis. Severe pain, and stiffness in the lumbar region, when seated or when walking. Pain in the lumbar region , with drawing pains around the thighs. Drawing pains in the sacrum , ameliorated by urinating or expelling wind, worse when standing.

Ferrum metallicum
Partial immobility of the arm and slight ankylosis of the wrist.

Kalium iodatum
Weakness, emaciation. Arteriosclerosis. Cachexia. Contraction of muscles and tendons, chronic arthritis with spurious ankylosis.

Mercurius solubilis
Local signs of inflammation, marked deformity, extreme atrophy of muscles, swelling of soft parts, subcutaneous nodules, fibrous or bony ankylosis. Marked deformity, extreme atrophy of muscles, swelling of soft parts, subcutaneous nodules, fibrous or bony ankylosis. Marked pain.

Paralysis of spine, especially the sacrum, from spondylitis. The chest becomes rigid or immovable. Pain, heat and burning in the spine and sciatic nerve. Sensitive, tender spinous process – especially the dorsal spine. An important remedy in ankylosing spondylitis with rigid spine and fixed chest wall. Worse: Cold. Rising from a seat. Lying on the left side.  Laughing. Crossing the legs in bed. Better: Heat. Lying on right side or on back. Rubbing. Motion.

Radium bromatum
In Europe, Ra-224 [isotope with a half-life of about three and a half days] was used for more than 40 years in the treatment of tuberculosis and ankylosing spondylitis. The treatment of children was abandoned in the 1950s, but the ability to relieve debilitating pain from ankylosing spondylitis in adults has prolonged its use.

Rhus toxicodendron
Numbness and formication, after overwork and exposure. Tension as from shortening of muscles. Numbness of limbs on which he lies; esp. arms. Stiff and paralysed sensation in joints from sprains, over-lifting and over-stretching. Of internal coldness in limbs. As if skin around diseased parts were too tight. PA Tearing, in tendons, ligaments and fasciae. Rheumatic, spread over a large surface at nape, loins, and limbs; amel. motion [Agar.]. Soreness of condyles of bones. 5 Rheumatic gnawing, & desire to move limbs frequently, which amel.. Drawing or tearing, in limbs during rest. OB Hot, painful swelling of joints. Limbs stiff, paralysed. Paralysis; trembling after exertion. Paraplegia; after parturition; sexual excess; fevers. Lameness, stiffness and pain on first moving after rest, or on getting up in morning; amel. continued motion; but soon fatigued, requiring rest again. Cold hands and feet. Cracking of joints when stretched. Synovitis; spurious ankylosis.

Sarcolacticum acidum
Cramping pains predominantly in the back and lumbar region, aggravated when standing. At the extremities : cramp, paraesthesia, articular numbness and pains. Difficulty in brushing hair. Tiredness of the wrist when writing. Ankylosis , muscular contracture and jerking, paresis (partial paralysis) when trying to climb.

Silicea terra
Synovial cysts.  Enlarged bursa over patella.  Large cyst on patella; not inflamed but extremely sensitive.  Chronic synovitis of knee with great swelling and ankylosis. Icy coldness of feet; or foot-sweat, often very offensive; or suppressed foot-sweat.

Thuja occidentalis
Here, Dr Nancy Malik provides some case histories using this remedy.

Spinal Curvature - The spine from the fifth to the twelfth vertebra bent backwards, the lung dorsal muscles in the region atrophied. The patient, a boy, aged eleven, cannot stand erect, is bent forward and supports his body by putting his hands upon his knees. When sitting upon a chair, he supports himself by holding fast to the back of the chair; when sitting upon the floor, his head sinks down upon his knees. His hair is thin and of slow growth; the urethra is reddened; his belly is enlarged (pot-bellied) and his nose is always stopped up. I gave Thuja 3c. A month after this he was much better; he moves about more handily and can sit erect in a chair for a short time; the improvement continued, but the restoration of the back to the normal state took about two years. C. Kunkel.

Paralysis- A woman, aged twenty-two, of feeble constitution and earthy, pale countenance came to me with stooping gait and faltering steps. Since her fourteenth year, she has had frequent vomiting and water-brash. For two months the vomiting has ceased and she now complains of her back and legs being very weak, almost paralyzed; her eyesight is very poor and she can only read a line at a time. For some time past she has had urinary tenesmus and incontinence. Menstruation has always been irregular and is sometimes suppressed; she often has leucorrhoea. Thuja 30th first relieved the urinary symptoms, then the leucorrhoea and menstruation returned regularly. Then the paralytic symptoms were much relieved and there developed much desquamation of the skin. In four months the patient was well, except slight anæsthesia of the legs. Dr. Rueckert.

Tuberculinum residuum Koch
Acts primarily on the fibrous tissues and produces fibro-chondro-osteo-mesenchymatic sclerosis! Lean weak people with grey colour of face and blue lips. Cicatrices. Dupuytren’s contraction. Chronic rheumatism with ankylosis. Periarthritis. Arthrosis. Ankylosis of the vertebral column. Tubercular rheumatism.

Viscum album
Arthrosis. Painful post-traumatic osteoporosis, linked with vaso-motor and tropho-cutaneous complaints. Dupuytren’s disease. Periarthrosis of the scapula and humerus. Arthrosis of the hip. Ankylosing spondylitis. Gonococcal rheumatism. Juvenile growth disorders.

Wiesbaden aqua
Rheumatism and gout. Abdomen full and tense. Passive or atonic gout. Contractions of muscles and tendons. Complete ankylosis. Stiffness of old fractures.